Genomics Project Leader
European Molecular Biology Laboratory
Cambridge, UK
1d ago

We are seeking an experienced project leader for activities and resources supporting model organism genomics at the European Bioinformatics Institute (EMBL-EBI).

Mice, rats, zebrafish, flies, worms and yeast are studied extensively by scientists around the world to gain fundamental insights into human biology.

The Alliance of Genome Resources (AGR, ) is a major new initiative to develop shared infrastructure, analysis pipelines and data curation workflows for 6 major Model Organism Databases(MODs) and the Gene Ontology (GO).

WormBase (), a founding member of the Alliance, is dedicated to providing integrated information on the genetics and genomics of the model organism Caenorhabditis elegans.

You will lead a team that acts as the genomics and hub for AGR and WormBase. The team’s responsibilities range from designing and deploying large-scale data integration and genome analysis pipelines, to curating the canonical reference genome and annotation for C.

elegans. The team also collaborates closely with the Wellcome Sanger Institute to produce WormBase ParaSite (), which uses the Ensembl platform () to provide access to hundreds of genomes for parasitic worms that damage human health and food supply.

You will be part of the Eukaryotic Annotation Team (led by Kevin Howe), which itself is part of a wider cluster of resources that includes Ensembl (led by Paul Flicek).

EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and is Europe's leading provider of information services to biological researchers in academia and industry.

Your role

Under the supervision of the Team Leader, will operationally lead our contribution to the Alliance of Genome Resources, WormBase, and WormBase ParaSite.

You will work closely with peers at international partner sites to ensure that the overall goals of these projects are met.

Your specific responsibilities will include :

  • Line management of a team of 5-7 bioinformaticians, developers and curators
  • Leading the development of genomics data analysis and integration pipelines for the Alliance of Genome Resources and WormBase
  • Project management for the provision of parasitic worm genomics data via the Ensembl platform
  • Leadership of the curation effort for the reference genome and annotation for C. elegansand selected other nematodes
  • Engagement with relevant scientific communities
  • Writing publications and reports
  • Representing the project(s) at meetings and conferences
  • You have

    You will hold a PhD or equivalent in bioinformatics or a related field and have at least three years post-graduate professional experience.

    Specifically, you will have :

  • Broad practical knowledge of genomic analysis techniques and tools
  • Detailed knowledge of genome annotation methodologies
  • Practical experience with using databases for modelling complex biological data (knowledge of graph databases will be considered a plus)
  • Excellent written and verbal communication skills
  • Previous experience with management or mentoring
  • You might also have

    The ideal candidate might also have experience with :

  • Model organism genetics
  • Working with the Ensembl platform
  • Writing software in Python or Perl
  • Working within international consortia
  • Formal project management tools / techniques
  • Why join us

    At EMBL-EBI, we help scientists realise the potential of big data’ in biology by enabling them to exploit complex information to make discoveries that benefit mankind.

    Working for EMBL-EBI gives you an opportunity to apply your skills and energy for the greater good. As part of the European Molecular Biology Laboratory (EMBL), we are a non-profit, intergovernmental organisation funded by over 27 member states and two associate member states.

    We are located on the Wellcome Genome Campus near Cambridge in the UK, and our 850 staff are engineers, technicians, scientists and other professionals from all over the world.

    EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.

    The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation.

    For more information about pay and benefits please click

    We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise something you probably won’t find anywhere else.

    If you’ve ever visited the campus you’ll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside.

    Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

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