Bioinformatics Workflow Developer
Oxford Nanopore Technologies
Oxford, Oxfordshire, United Kingdom
6d ago

Job Description

The Customer Analysis Workflows group and Oxford Nanopore Technologies' is responsible for presenting bioinformatic analyses to end users through various modes of presentation from software libraries, notebook tutorials, through to fully automated analyses on the EPI2ME platform.

The Details...

Reporting to the Director Analysis Workflows, the successful candidate will be driven to provide scientific analysis, software friendly to a range of user abilities.

You will be responsible for developing and maintaining new bioinformatic analyses to be coupled with particular experiment scenarios, targetting particular scientific and clinical questions.

You will work with other members in the team to create workflows that can be utilised across modes of presentation from standalone libraries and command line tools, to integrated graphical solutions.

Duties :

  • to build and maintain bioinformatics workflows to answer specific scientific and clinical questions
  • take ownership of newly identified workflows and work with others within the group to determine how best to present these to end users
  • liaise with groups within the various R&D groups at ONT to identify analysis workflows potentially useful to customers
  • adapt standard bioinformatic tools to long-read nanopore sequencing
  • identify areas for tool development, and work with Algorithm Research staff to explore options
  • define and promote best-practices for ONT’s open-source analysis software
  • maintain abreast of external advances in the field of long-read data analysis and the requirements of end-users as determined by various ONT’s customer facing staff
  • What We're Looking For...

    You will hold at least a MSc (or equivalent experience) involving a substantial amount of programming in a high-level language.

    A PhD or industry experience requiring understanding of DNA / RNA sequencing analysis is desirable.

    In addition you will be able to demonstrate :

  • experience in software development on Debian-based linuxes
  • expertise in bioinformatics workflows and knowledge of workflow management software (CWL, snakemake, nextflow)
  • practical experience of handling sequencing data with exposure to common software (samtools, bcftools)
  • familiarity with long-read sequencing
  • strong Python programming skills (development, testing, packaging)
  • familiarity with continuous integration and deployment
  • a willingness to adapt, listen and learn new skills
  • Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation.

    Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

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