Structural Bioinformatics Research Scientist
Oxford, England
1d ago

Exscientia is at the forefront of Artificial Intelligence (AI) driven drug discovery and the only company to successfully design drug molecules entirely by AI that are in clinical studies.

As a full stack AI Pharmatech, we are capable of generating our own experimental data to complement the analytical power of AI and the creativity and expertise of our world-class scientists.

We aim to revolutionise the pharmaceutical industry by significantly shortening the preclinical drug discovery stage to accelerate new treatments to patients globally.

Exscientia is looking for extraordinary people to join its extraordinary mission : to revolutionise the way new medicines are discovered.

Following multiple high-profile partnerships and our most recent fundraise we are now adding a key appointment to our group, Research Scientist - Structural Bioinformatics .

This position is integral to support the Company’s growing array of projects and appetite for scientific innovation.We are looking for an excellent Research Scientist - Structural Bioinformatics to work closely with our team of drug designers and software engineers to develop and implement novel structural informatics techniques and algorithms.

You will have the opportunity to

  • Develop structural bioinformatics algorithms and implement research prototypes to test their impact on our drug discovery programs.
  • Work with drug designers to translate feedback back into algorithmic improvements.
  • Work with software engineers to implement these algorithms into our technology platform.
  • Stay informed on new technology developments, analyse them for potential benefits to our platform and devise plans for their implementation.
  • What will you bring to the role?

  • Degree in chemistry, bioinformatics or a related field or a degree in computer science with the structural bioinformatics knowledge stemming from extensive professional experience.
  • Proven track record of developing and implementing novel structural bioinformatics algorithms.
  • Software development experience to efficiently design and implement modules, packages, applications and APIs.
  • Proficiency in Python
  • Writing and maintaining unit tests, creating high-quality documentation.
  • Excellent interpersonal, oral, and written communication skills
  • Strong team player with an inclusive mindset that is willing to listen and learn from others.
  • Passionate about the idea of discovering novel therapeutics by application of technology.
  • Desirable Skills

  • Experience working with relational databases.
  • Knowledge in homology modelling across different protein classes
  • Experience working on druggability and target tractability assessments
  • Experience working directly with crystallographic data
  • Open source contributions or publications in academic journals demonstrating experience in scientific software development.
  • Experience working on active small molecule drug discovery projects
  • Experience in one of the major cheminformatics toolkits (RDKit, OpenEye etc.)
  • What will you get from us?

  • Making a positive contribution to patients by revolutionising the pharmaceutical industry through AI driven discovery
  • Joining a scaling AI organisation with world class technical and scientific leaders
  • An opportunity to grow your career with us as we grow our organisation
  • We offer a highly competitive compensation to support our employees as we continue to grow and thrive
  • The opportunity to join an inclusive, collaborative and intellectually stimulating culture
  • Working in modern offices with fantastic free food on offer
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