(SENIOR) SCIENTIST - LNP DISCOVERY - UK
Nanovation Therapeutics
Bicester, Oxfordshire, England
1d ago

ABOUT NANOVATION

NanoVation Therapeutics, founded in 2020, is a private biotechnology company focused on developing customized lipid nanoparticle (LNP) solutions for industrial and academic gene therapy applications.

In 2021, NanoVation expanded to the UK, creating a global network of world-leading LNP knowledge and expertise. Our mission is to see the full potential of these game-changing technologies realized.

NanoVation UK is committed to creating an inclusive, diverse, and supportive work environment. Our values are integrity, honesty, accountability, and continued learning.

NanoVation offers a competitive salary and benefits package.

HARWELL, UK

NanoVation UK is based at the Research Complex at Harwell (RCaH), itself an integral part of the UK’s leading science and innovation campus at Harwell.

Home to a diverse mix of research hubs, academic groups and SMEs, and next door to world-leading scientific facilities (Diamond Light Source, ISIS Muon and Neutron Source, Rosalind Franklin Institute and the ESA), RCaH offers an unparalleled environment for creativity, innovation and discovery.

Set in the beautiful Oxfordshire countryside and with a wide range of on-site sports and recreation facilities, Harwell campus is 30 mins drive from Oxford and just over an hour commute from central / west London by rail.

JOB DESCRIPTION

We are looking for ambitious scientists with a strong foundation in nanomedicine formulation and pre-clinical evaluation.

You must be passionate about enabling and accelerating the clinical translation of gene therapies.

Reporting to the Managing Director / Director of Science, you will be primarily responsible for designing and executing protocols related to internal discovery pipelines or partner-based projects.

You will be responsible for the production and analysis of formulations, designing and conducting pre-clinical in vitro studies , documentation of experiments and outcomes, communication with external (partners) and internal (project teams) stakeholders to transfer processes and methods for further development, providing research plans, experimental design, technical documents, reports.

Additional tasks could be assigned as necessitated by day-to-day operations.

NanoVation Therapeutics UK is seeking to fill 2 positions based on this job description. Compensation will be commensurate with the candidate’s level of degree and years of experience.

QUALIFICATIONS

MSc or PhD in Pharmaceutical Sciences, Chemistry or a Life Science discipline with a minimum of 2 years experience in drug / gene delivery, or an equivalent combination of a degree and hands-on’ experience (e.

g. BSc with 4 years experience). Postdoctoral experience is an asset.

Hands-on experience of preclinical nanomedicine development including :

i) Lipid-based drug delivery and formulation, including microfluidic procedures,

ii) Formulation characterization, including particle size and zeta potential measurements, pKa determination, UV-Vis and fluorescence measurements.

iii) Preclinical in vitro testing of drug formulations, including cell-based assays and analytical techniques to assess safety and performance.

Strong technical knowledge of nucleic acid-based drug delivery technologies.

A strong track record of scientific publications

Strong written and oral communication skills

Excellent interpersonal skills, initiative, and flexibility

Good organization skills, time management, and ability to prioritize

Self-driven, able to think critically and make decisions

Right to work in the UK is strongly preferred.

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