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We are currently recruiting for a Scientist IV to join our Vector Engineering Group. The purpose of this role is to plan, execute and report laboratory-based experiments or analytical investigations in accordance with scientific or regulatory requirements, in alignment with department objectives
Your responsibilities in this role would be :
To undertake laboratory projects within the Vector Innovation Team towards improved lentiviral vector design
Technically support broader projects within the Vector Innovation Team and wider Vector Engineering and Platform Research Groups as required
To be able to work independently and collaboratively according to the requirements of the project
To maintain knowledge in the field through scientific literature and conferences, and to report back items of interest accordingly
Accountable for own performance in alignment with group objectives and deadlines. Design and conduct experiments / investigations in accordance with correct methodologies and procedures under the direction of the Group Lead.
Ensure a high standard of record keeping and documentation of experiments and investigations in order that information is clearly captured and disseminated and reported.
Present scientific data at internal meetings and external venues such as conferences.
Will report to the Group Leader or his / her delegated grade 5 to 6 scientist.
Conduct research and technical support of the highest quality, largely in a single project area but will assist in other projects as the need arises.
Ensure correct training requirements are met and that the training record is kept correct and up to date
Ensure experimental data is submitted to PatentSafe in a timely manner.
May be responsible for maintenance of a laboratory area and / or important equipment.
Personally responsible for the completion of tasks in relation to their criticality.
Joint responsibility for maintenance and compliance of a GxP laboratory area and GxP housekeeping procedures.
Work will be conducted in accordance with the OXB quality management system.
Writing and reviewing of departmental documentation and SOP’s.
Preparation of reports and documents to support GxP and regulatory activities.
To be successful in this role, you will have the following skills and experience :
PhD or BSc / MSc Degree in an appropriate discipline with relevant post-qualification experience
Knowledge in Virology and gene therapy would be an advantage
Laboratory experience with particular emphasis on one or more of the following : Tissue Culture, qPCR, Molecular Biology, flow cytometry and handling virus / viral vectors
Demonstrate competency in performing laboratory tasks and general experimental procedures with expertise in protein purification.
Trained to operate equipment in accordance with OXB procedures and requirements. Responsibility for a single piece of equipment and the ability to troubleshoot.
Expertise in the use of complex instrumentation eg qPCR, FACS or using difficult biological procedures that requires a specialist knowledge or skill.
Understanding of laboratory health and safety requirements.
Sufficient understanding of the overall activities in the department to contribute useful ideas at meetings.
Familiar with the literature relating to project area.
Capable of interpreting results from experiments and drawing conclusions but may need guidance from senior scientists.
Capable of explaining clearly why an experiment is being conducted and how the experiments help the group meet their objectives.
Good knowledge of the overall research programme in your group.
Competent in the use of PatentSafe system that operates at OXB and submission of documents to PatentSafe in a timely manner.
Detailed knowledge of the Quality management reporting structure / responsibilities within OXB.
High regard for safety and display a high level of good laboratory citizenship.
Detailed knowledge of the regulatory requirements for analytical work (e.g. product specifications, stability testing guidelines etc) is required.
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