DMPK Group leader
Cancer Research UK
CRT Cambridge (Babraham), GB
2d ago

DMPK Group leader

  • CRT Cambridge (Babraham)
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    DMPK Group Leader CRUK Drug Discovery

    Location : Cambridge, Babraham research campus

    Salary range : £65,000-£75,000 dependent on experience

    This is a full-time role.

    We encourage flexible working and we can offer home-working 1-2 days per week.

    We seek to recruit a passionate individual to lead the DMPK group based at our Babraham Research Campus facilities in Cambridge, that will provide support across CRUK’s multiple drug discovery sites.

    This is an exciting opportunity to work with cross-functional teams both internally and externally to develop drugs to improve the lives of cancer patients.

    About CRUK drug discovery

    We're in the process of changing the way we support preclinical therapeutic discovery and development and we're establishing a world-class drug discovery organisation across our multiple drug discovery sites.

    Further details on this will be shared soon.

    We have a major focus on establishing and prosecuting biologically-themed multi-project alliances with industrial partners, or through creation of new companies.

    Based at the Babraham Research Campus, Cambridge, the Beatson Institute in Glasgow and the Francis Crick Institute, London, CRUK drug discovery comprises 150 staff from both industrial and academic


    We bring together the best minds in basic and clinical cancer research, the diligence and drive of pharmaceutical and biotech companies, and our in-house drug discovery and alliance management capabilities to deliver breakthrough medicines for cancer patients.

    Our laboratories house the personnel and state of the art equipment required to progress projects from initial hypothesis through to selection of candidate drugs for regulatory development.

    We couple this with a deep understanding of academic and industrial drivers, enabling us to build alliances that combine the curiosity of basic research and the rigour of drug discovery.

    Who are we looking for

    Candidates should have a strong background in DMPK and leading teams in a drug discovery environment.

    To be considered for the position, it is highly desirable that you have the following skills and experience :

    Qualified to PhD level in a Life Sciences discipline as well as extensive experience in drug metabolism, bioanalysis, pharmacokinetics and pharmacokinetic / pharmacodynamic modelling.

    Good time management skills, a proven ability to form close and effective relationships with colleagues at all levels (both internal and in partner organisations) and excellent written and verbal communication skills.

    A track record of working on diverse projects, delivering compounds to pre-clinical and clinical development.

    Proven experience of using cutting edge approaches to compound profiling and prediction of human dose and PK parameters.

    An excellent knowledge of all aspects of ADMET and PK to influence experimental design and data interpretation across a range of projects.

    Experience of working on projects at all stages of drug discovery from hit to lead to the clinic.

    Experience of managing in vitro and in vivo outsourcing.

    You can find out more by viewing this candidate pack.

    What we can offer you

    Competitive benefits package. Salary £65,000-£75,000.

    Option to access the CRUK pension scheme where CRUK will contribute up 12% of your salary.

    Opportunities for professional development and conference attendance.

    A beautiful setting to work in at the Babraham Research Campus with access to campus facilities such as gym, tennis court, on-site restaurant and country walks.

    Being part of a vibrant team committed to beating cancer.

    At CRUK we value diversity and we're committed to creating an inclusive culture where everyone is able to be themselves and to reach their full potential.

    We actively encourage applications from people of all backgrounds and cultures and believe that a diverse workforce will help us to beat cancer sooner.

    Unfortunately we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.

    Should you need any adjustments to the recruitment process, at either application or interview, please contact us on recruitment


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