Research Fellow
Brunel University London
London, UK
2d ago

Salary (Grade) : £35,365 to £41,775 pa incl. London Allowance

We are looking for an enthusiastic and driven post-doctoral fellow to join the Chromosome structure and dynamics laboratory led by Professor Paola Vagnarelli in Brunel University London.

The programme is funded by the Wellcome Trust to investigate protein phosphatases involved in Cell division. Using a combination of genetic, biochemistry and cell biology approaches, the projects aim to identify the main substrates of different phosphatase complexes during mitotic exit, how they modify chromatin architecture and their mitotic and non-mitotic roles.

This represents a great opportunity for ambitious scientists to use cutting edge approaches including live cell imaging, mass spectrometry, transcriptomics and genome editing.

  • Duties and responsibilities of the post holder include but are not limited to : plan, perform, analyse and interpret experimental data under the direction of the grant holder, Professor Paola Vagnarelli;
  • liaise effectively and pleasantly with other members of the research team, collaborators and other internal and external investigators to achieve the post-

    objectives; plan experiments and record results in a lab book and electronic records; design and perform experiments including cell culture, RNA purification, genome engineering, ChIP-

    seq and ChIP-qPCR, affinity purification, western blotting and cloning.

    The successful candidate must have a PhD in Molecular biology, Biochemistry, Cell biology, or a related subject.

    Candidates must have experience in cell and molecular biology techniques, ability to design well-controlled experiments and present data clearly through well-

    designed figures; ability to use and understand statistics to interpret data are also among essential criteria; authorships of papers in relevant research areas, either published or under review and bioinformatics skills (including scripting in Bash, R, Perl or Python) are desirable criteria.

    Brunel University London is an upcoming and leading multidisciplinary research-intensive technology university where Research Institutes and College Centres foster a positive research culture.

    Closing date for applications : 27 May 2019

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