Exscientia is at the forefront of Artificial Intelligence (AI) driven drug discovery and the only company to successfully design drug molecules entirely by AI that are in clinical studies.
As a full stack AI Pharmatech, we are capable of generating our own experimental data to complement the analytical power of AI and the creativity and expertise of our world-class scientists.
We aim to revolutionise the pharmaceutical industry by significantly shortening the preclinical drug discovery stage to accelerate new treatments to patients globally.
Exscientia is collectively working to build a cutting-edge future and we are looking for like-minded individuals to join our journey.
Following multiple high-profile partnerships and our most recent fundraise we are now adding a key appointment, Head of New Target Validation .
Exscientia has developed a ground-breaking approach to target identification, Centaur Biology. By applying deep learning to comprehensive knowledge graphs, our Target Analysis team use this approach to identify emerging drug targets.
The Head of New Target Validation will lead a team to deploy cutting-edge genetic and pharmacological approaches to interrogate these targets to provide an understanding of their role in signalling and functional pathways, and ultimately in disease.
The disease focus of the work will be in oncology and immunology. Based at our brand-new labs in Oxford, the successful candidate will lead the target validation group strategy, developing both internal and external capabilities for these purposes, including recruiting and leading a team of drug target validation biologists.
Your team will provide critical data and insights to target selection for the company portfolio and provide support and cellular reagents to therapeutic project teams to execute drug discovery projects.
You will have the opportunity to use your experiences in drug discovery to provide leadership to therapeutic projects.We are looking for an outstanding leader with deep expertise in genetic technologies for target validation to drive the adoption of targets into Exscientia’s drug discovery portfolio.
Based on emerging targets from Centaur Biology and other approaches, you will generate target validation datasets to create therapeutic hypotheses, with the aim of initiating drug discovery projects in the areas of oncology and immunology.
These datasets will include signalling and functional assay endpoints from genetic and pharmacological studies in relevant cellular systems.
You will use your expertise and experience in drug discovery to provide an understanding of target tractability and translation through disease.
You will work closely with the Target Analysis team to provide a pipeline of informed targets for Exscientia’s discovery platform.
It is anticipated that you will provide leadership to internal and external therapeutic projects.
What will you be doing in this role?
What will you bring to the role?
What can you expect from us?