Kennedy Institute of Rheumatology, Old Road Campus, Oxford, OX3 7FY Grade 7 : £32,817 - £40,322 p.a. The lab of Associate Professor Steve Sansom (https : / / sansomlab.
org) at the University of Oxford is looking for a highly motivated computational biologist. Our research is focused on identifying the cellular and molecular causes of immune-mediated inflammatory disease (IMID) using systems-level approaches.
We now have an exciting opportunity for a talented scientist to join the group to help lead research into the cellular basis of rheumatoid arthritis, a common and long-term autoimmune disease that attacks the joints.
The work will involve modelling state-of-the-art single-cell and spatial-genomics datasets from developing human synovial joints with the goal of generating novel insights into the origins and molecular mechanisms of pathogenic and reparative stromal and immune cell subsets.
The successful applicant will join a team of computational biologists, clinicians and experimental scientists that is led by Professor Chris Buckley, Professor Mark Coles and Associate Professor Steve Sansom.
They will participate in the Human Cell Atlas project. You should have a successful track record in academic research that includes the statistical analysis and interpretation of complex genomic datasets, excellent problem-solving abilities and a strong interest in inflammatory disease research.
A PhD / DPhil (or near completion) in a discipline of direct relevant to computational single cell genomics research is essential.
In this role you will perform scientific research, reviewing and refining working hypotheses and developing and acquiring relevant skills as necessary.
You will analyse and interpret data, preparing and publishing your findings in peer-reviewed journals. Experience with the analysis of single-cell RNA-sequencing data is highly desirable.
The successful applicant will be based at the Kennedy Institute of Rheumatology within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences.