Applications are invited for a 6-month research associate contract in the laboratory of Dr Paul Miller at the Department of Pharmacology, University of Cambridge.
More information about the laboratory is available at https : / / www.phar.cam.ac.uk / research / miller. We are looking for a motivated and innovative scientist to carry out a research project to establish a robust GABAA receptor structural biology platform for high resolution observation of drug binding modes.
Specifically the project will involve solving structures bound by drugs to precisely (i.e. to high resolution) reveal the binding modes.
The role holder will be located in the Cambridge area. The key duties and responsibilities will include, but are not limited to : developing research objectives and conducting the research project, writing up research work for presentation and publication, continually updating knowledge and understanding in the research field, translating knowledge of advances in the subject area into research activity, managing own research and administrative activities, assisting in the preparation of proposals and applications to external bodies (e.
g. for funding and contractual purposes), communicating material of a specialist or highly technical nature.
The applicant must hold a PhD in the field of structural biology. Successful candidates will be expected to have demonstrable experience in protein purification, crystallisation, and independently processing datasets to deposition (e.
g. PDB) standard. Experience in electron microscopy techniques such as negative stain and cryo-EM, as well as analysing protein-
ligand interaction through biophysical techniques (e.g. ITC, Thermofluor) are an advantage. Experience in the field of GABAA receptor structural biology is an advantage.
You must be a careful and methodical worker, paying attention to accuracy and ready to take responsibility as part of a team.
You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction.
The funds for this post are available with effect from 1st March 2018. The salary range is £30,395 - £39,609 per annum.
Fixed-term : The funds for this post are available for 6 months in the first instance.
Informal enquiries about the position can be made to Dr Paul Miller (pm676 cam.ac.uk)
The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects.
We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates.
Appointment will be based on merit alone.
Applications will be assessed as and when they are submitted and it is anticipated that interviews will take place on the 19th of December